Kalinina E I, Gaginskaia E R
Tsitologiia. 1983 Dec;25(12):1370-7.
3H-thymidine incorporation into the fowl oocytes was established radioautographically at the middle preleptotene, when chromosomes are condensed and associated in the complex chromocenters. According to the cytophotometry of Feulgen stained oocyte nuclei, their DNA value increases during preleptotene from 2 to 4c. So, the DNA synthesis observed is characteristic of chromosome reduplication, rather than of nuclear organizer amplification. The preleptotene should be considered as the initial stage of meiotic prophase because it involves spiralization and individualization of chromosomal threads. Both the analysis of literary data and of our own results enable us to conclude that in different species the meiotic chromosome reduplication may proceed in different periods between telophase of last gonial mitosis and the beginning of homologous chromosome conjugation.
通过放射自显影法确定，在细线前期中期，当染色体浓缩并在复合染色中心缔合时，3H-胸腺嘧啶核苷掺入禽卵母细胞。根据福尔根染色的卵母细胞核的细胞光度测定，其DNA值在细线前期从2c增加到4c。因此，观察到的DNA合成是染色体复制的特征，而不是核仁组织区扩增的特征。细线前期应被视为减数分裂前期的初始阶段，因为它涉及染色体丝的螺旋化和个体化。对文献数据和我们自己结果的分析都使我们能够得出结论，在不同物种中，减数分裂染色体复制可能在最后一次生殖细胞有丝分裂末期和同源染色体配对开始之间的不同时期进行。
