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聚焦重叠超声场诱导的局部热疗——一项体内演示。

Local hyperthermia induced by focussed and overlapping ultrasonic fields--an in vivo demonstration.

作者信息

Hynynen K, Watmough D J, Mallard J R, Fuller M

出版信息

Ultrasound Med Biol. 1983 Nov-Dec;9(6):621-7. doi: 10.1016/0301-5629(83)90007-8.

DOI:10.1016/0301-5629(83)90007-8
PMID:6670147
Abstract

Axial temperature distributions were measured in living and post mortem porcine tissues during sonication with plane, focussed and overlapping ultrasonic fields. With the focussed field it was always possible to induce the temperature maxima at depths up to 50 mm, although the actual temperatures achieved varied from animal to animal. The plane 0.75 MHz transducer produced a maximum temperature close to the skin surface. With 7 overlapping plane fields a relatively uniform temperature distribution was produced in a large tissue volume. The blood perfusion in tissue has a significant effect not only on the magnitude of the temperature increase, but also on the temperature distribution.

摘要

在使用平面、聚焦和重叠超声场进行超声处理期间,测量了活体和死后猪组织中的轴向温度分布。使用聚焦场时,总是可以在深度达50毫米处诱导出温度最大值,尽管不同动物实际达到的温度有所不同。0.75兆赫的平面换能器在皮肤表面附近产生了最高温度。使用7个重叠的平面场时,在较大的组织体积中产生了相对均匀的温度分布。组织中的血液灌注不仅对温度升高的幅度有显著影响,而且对温度分布也有显著影响。

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