Gordon B R, Saal S D
Clin Exp Dial Apheresis. 1983;7(3):169-76. doi: 10.3109/08860228309076046.
Four patients with post-partum hemolytic uremic syndrome were treated with plasma exchange using fresh frozen plasma as replacement. Each patient had microangiopathic hemolysis, thrombocytopenia, and progressive renal and hepatic failure. Disseminated intravascular coagulation was a major feature in each case. The microangiopathy and thrombocytopenia resolved in each patient following plasma exchange. Normalization of renal and hepatic function occurred in three patients, including one patient who died as a result of coronary artery dissection. One patient died as a result of an intracerebral bleed. Plasma exchange with fresh frozen plasma replacement appears to be of benefit if used early in the course of post-partum hemolytic uremic syndrome.
4例产后溶血性尿毒症综合征患者接受了以新鲜冰冻血浆作为置换液的血浆置换治疗。每位患者均有微血管病性溶血、血小板减少以及进行性肾和肝功能衰竭。弥散性血管内凝血是每例患者的主要特征。血浆置换后每位患者的微血管病和血小板减少均得到缓解。3例患者的肾和肝功能恢复正常，其中1例患者死于冠状动脉夹层。1例患者死于脑出血。在产后溶血性尿毒症综合征病程早期使用以新鲜冰冻血浆作为置换液的血浆置换似乎有益。
