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产后溶血尿毒综合征诊断为重度子痫前期 1 例。

A case of severe preeclampsia diagnosed as post-partum hemolytic uremic syndrome.

机构信息

Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China.

出版信息

Chin Med J (Engl). 2012 Mar;125(6):1189-92.

Abstract

Post-partum hemolytic uremic syndrome (PHUS) is a severe thrombotic microangiopathy clinically characterized by hemolytic anemia, renal dysfunction, and low platelets after birth with rapid progression and poor prognosis. Here, we reported a rare case of severe preeclampsia diagnosed as hemolytic uremic syndrome after birth. The patient was diagnosed with PHUS and underwent intermittent plasma exchange with supportive treatment including glucocorticoid injections and transfusion of suspended red blood cells. After these treatments, the patient experienced no apparent remission and chronic renal dysfunction occurred on her. PHUS is a severe emergency with acute onset, rapid progress, and poor prognosis. Early detection, diagnosis, and treatment can significantly improve the prognosis.

摘要

产后溶血尿毒综合征(PHUS)是一种严重的血栓性微血管病,其临床特征为产后迅速进展、预后不良的溶血性贫血、肾功能不全和血小板减少。本研究报道了一例罕见的重度子痫前期病例,产后诊断为溶血尿毒综合征。患者被诊断为 PHUS,给予间歇性血浆置换联合支持治疗,包括糖皮质激素注射和悬浮红细胞输注。经治疗后,患者病情未见明显缓解,且出现慢性肾功能不全。PHUS 起病急骤,进展迅速,预后差。早期发现、诊断和治疗可显著改善预后。

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