Klein L, Eichelberger H, Mirian M, Hiltner A
Connect Tissue Res. 1983;12(1):71-8. doi: 10.3109/03008208309005613.
Collagen fibers (bundles of fibrils) of rat small intestine as observed by Nomarski differential interference contrast microscopy were densely packed in parallel undulating arrays. At the electron microscopical level the diameters of intestinal collagen fibrils increased gradually from 50 nm at three weeks of age to 80 nm at 12 months of age. At each age the fibril diameters were fairly uniform in size. At three weeks or six months of age collagen fibrils from stretched, salted samples were somewhat larger in diameter (12-16%) than those from unstretched, unsalted samples. A biaxial orientation existed between bundles of collagen fibrils at angles that varied from 32 degrees to 81 degrees with a mean of 60 degrees. Thus, intestinal collagen at the fibril level is aligned at varying angles to the longitudinal and circular directions of the intestine.
用诺马斯基微分干涉相差显微镜观察到的大鼠小肠胶原纤维（原纤维束）紧密排列成平行起伏的阵列。在电子显微镜水平上，肠胶原原纤维的直径从3周龄时的50纳米逐渐增加到12月龄时的80纳米。在每个年龄阶段，原纤维直径在大小上相当均匀。在3周龄或6月龄时，拉伸、盐处理样品中的胶原原纤维直径比未拉伸、未盐处理样品中的稍大（12%-16%）。胶原原纤维束之间存在双轴取向，角度在32度至81度之间变化，平均为60度。因此，在原纤维水平上，肠胶原与肠的纵向和环向呈不同角度排列。
