Komuro T
Department of Anatomy, School of Medicine, Ehime University, Japan.
Cell Tissue Res. 1988 Jan;251(1):117-21. doi: 10.1007/BF00215455.
The three-dimensional architecture of the submucosal collagen fibres of the rat (3 weeks old) small intestine was examined by scanning electron microscopy using a selective microdissection method. The main framework of the submucosa was composed of two arrays of collagen fibre bundles running diagonally around the intestinal wall, one set in a clockwise direction, the other counterclockwise. These fibre bundles were about 5 micron diameter and were oriented at a range of angle +/- 30 degrees -50 degrees to the longitudinal axis of the intestine. With the advantage of the SEM observation it was demonstrated that these fibres in different arrays did not constitute two separate layers but interwove to form a unified lattice sheet. An irregular network of fine collagen fibrils over the main framework was also seen. The significance of their arrangement is discussed with respect to the skeletal function of the submucosa in the intestine.
采用选择性显微解剖法，通过扫描电子显微镜对3周龄大鼠小肠黏膜下胶原纤维的三维结构进行了研究。黏膜下层的主要框架由两组沿肠壁斜行排列的胶原纤维束组成，一组呈顺时针方向，另一组呈逆时针方向。这些纤维束直径约为5微米，与肠纵轴的夹角在±30度至50度范围内。利用扫描电子显微镜观察的优势，证实不同排列的这些纤维并非构成两个独立的层，而是相互交织形成一个统一的格子状薄片。在主要框架上还可见到由细胶原纤维构成的不规则网络。文中就黏膜下层在肠道中的支架功能对其排列的意义进行了讨论。
