Dibrov B F, Livshits M A, Vol'kenshteĭn M V
Biofizika. 1978 May-Jun;23(3):494-500.
A model of immune reaction is described which takes into account the agressive behaviour of infectious microorganisms in the macroorganism. The model allows a description of threshold relationship between the infection process and the initial dose of the antigen. According to the model depending on the parameters and initial data the following regimes are possible: destruction of the antigen without a disease, its destruction after a disease, coexistence of the antigen with specific antibodies, recurrent course of the disease, unlimited multiplication of the antigen.
描述了一种免疫反应模型，该模型考虑了感染性微生物在大生物体中的侵袭行为。该模型能够描述感染过程与抗原初始剂量之间的阈值关系。根据该模型，取决于参数和初始数据，可能出现以下情况：抗原在无疾病状态下被破坏、抗原在患病后被破坏、抗原与特异性抗体共存、疾病的复发过程、抗原的无限增殖。
