从长爪沙鼠（Meriones unguiculatus）的哈德氏腺获得的2,3 - 链烷二醇二酰基酯的表征。

The characterization of 2,3-alkanediol diacyl esters obtained from the Harderian glands of Mongolian gerbil (Meriones unguiculatus).

作者信息

Otsuru O, Otsuka H, Kasama T, Seyama Y, Sakai T, Yohro T

出版信息

J Biochem. 1983 Dec;94(6):2049-54. doi: 10.1093/oxfordjournals.jbchem.a134560.

DOI:10.1093/oxfordjournals.jbchem.a134560

PMID:6671980

Abstract

A major lipid class in the Harderian glands of the Mongolian gerbil was investigated. The IR and 1H-NMR spectra suggested that it was a wax-like compound. Fatty acids present were capric, lauric, myristic, palmitic, stearic, arachidic, and behenic acids in ratios of 3.0%, 16.3%, 16.5%, 29.5%, 5.1%, 16.4%, and 9.8%, respectively. Odd-numbered, branched chain and unsaturated fatty acids were not present in large amounts. The structure of the alcohol moiety was elucidated to be 2,3-alkanediol with carbon chain lengths from C12 to C22 by GC-MS of the TMS and isopropylidine derivatives. Lemieux-von Rudloff oxidation of these alcohols confirmed the 2,3-diol structure, giving fatty acids two carbon units shorter.

摘要

对蒙古沙鼠哈德氏腺中的一种主要脂质类别进行了研究。红外光谱和氢核磁共振光谱表明它是一种蜡状化合物。所存在的脂肪酸为癸酸、月桂酸、肉豆蔻酸、棕榈酸、硬脂酸、花生酸和山嵛酸，其比例分别为3.0%、16.3%、16.5%、29.5%、5.1%、16.4%和9.8%。奇数碳、支链和不饱和脂肪酸含量不多。通过对三甲基硅烷（TMS）和异亚丙基衍生物进行气相色谱 - 质谱分析，醇部分的结构被阐明为碳链长度从C12到C22的2,3 - 链烷二醇。这些醇的勒米厄 - 冯·鲁德洛夫氧化反应证实了2,3 - 二醇结构，生成的脂肪酸碳链缩短了两个碳单位。