Clerc N
J Auton Nerv Syst. 1983 Dec;9(4):623-36. doi: 10.1016/0165-1838(83)90118-2.
Labeling of afferent neurons by the retrograde axonal transport of horseradish peroxidase (HRP) was performed on anaesthetized cats in order to examine the afferent innervation of the lower oesophageal sphincter (LOS), involving both the vagal and the sympathetic nerves. The labeled cells, whose fibres follow the sympathetic pathways were found in dorsal root ganglia from T1 to L2. Nerve section experiments indicated that the main pathways involved were the splanchnic nerves, as expected from classical data. Additional pathways passing through the sympathetic cardiac branch emerging from the stellate ganglion and the thoracic sympathetic branches were also evidenced. This work corroborated the electrophysiological data showing the richness of the LOS sensory vagal innervation. Nevertheless, in this case the difficulties related to the HRP technique are particularly enhanced since the abdominal sensory vagal fibres can be affected by HRP injections.
为了研究食管下括约肌（LOS）的传入神经支配，包括迷走神经和交感神经，对麻醉的猫进行了辣根过氧化物酶（HRP）逆行轴突运输标记传入神经元的实验。在T1至L2的背根神经节中发现了其纤维沿交感神经通路走行的标记细胞。神经切断实验表明，主要涉及的通路是内脏神经，这与经典数据预期的一致。还证实了通过星状神经节发出的交感心脏分支和胸交感神经分支的其他通路。这项工作证实了电生理数据，显示了LOS感觉迷走神经支配的丰富性。然而，在这种情况下，由于腹部感觉迷走神经纤维可能会受到HRP注射的影响，与HRP技术相关的困难尤其突出。
