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用辣根过氧化物酶技术研究豚鼠下呼吸道脊髓传入神经支配的证据。

Evidence for a spinal afferent innervation of the guinea pig lower respiratory tract as studied by the horseradish peroxidase technique.

作者信息

Dalsgaard C J, Lundberg J M

出版信息

Neurosci Lett. 1984 Mar 23;45(2):117-22. doi: 10.1016/0304-3940(84)90085-5.

DOI:10.1016/0304-3940(84)90085-5
PMID:6728309
Abstract

The afferent innervation of the guinea pig lower respiratory tract was studied using a retrograde axonal transport technique with application of horseradish peroxidase (HRP) onto the lining respiratory epithelium. HRP-labeled cells were observed not only in the nodose ganglia but also in the jugular and upper thoracic dorsal root ganglia (mainly at the T2-T3 levels). Thus, both vagal parasympathetic and spinal sympathetic afferents seem to have peripheral branches close to or within the respiratory epithelium suggesting a dual sensory control of the airways.

摘要

利用逆行轴突运输技术,将辣根过氧化物酶(HRP)应用于豚鼠下呼吸道的衬里呼吸上皮,研究了其传入神经支配。不仅在结状神经节中观察到了HRP标记的细胞,而且在颈静脉和上胸段背根神经节(主要在T2-T3水平)中也观察到了。因此,迷走神经副交感神经和脊髓交感神经传入似乎都有靠近呼吸上皮或在呼吸上皮内的外周分支,提示气道存在双重感觉控制。

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