Gadzicki M, Krajewska B, Kubasiewicz S
Med Pr. 1983;34(5-6):405-12.
The study was aimed at evaluation of the dynamics of changes of ferrum balance parameters in patients acutely poisoned with some drugs and solvents. Altogether 19 persons were examined, in this 12 patients poisoned with drugs and 7 poisoned with solvents. The control group consisted of 20 persons. In all patients, on the first, second, third and last day of hospitalization, Fe concentration in blood serum was determined as well as latent capability of binding Fe by serum. Next, the total capability of Fe binding and coefficient of plasmatic transferine saturation with Fe were calculated. In case of drugs poisonings, statistically significant decrease of Fe concentration in serum on the second and third day of poisoning was found while no statistically significant differences were found in the other tested parameters during the first three days of hospitalization. In poisonings with ethylene glycol the tested parameters of ferrum balance are similar like the ones in drugs poisonings. The significant increase of Fe concentration was noted in cases of poisonings with such solvents as PER, TRI and TETRA.
该研究旨在评估某些药物和溶剂急性中毒患者铁平衡参数的变化动态。共检查了19人，其中12名药物中毒患者和7名溶剂中毒患者。对照组由20人组成。对所有患者在住院的第一天、第二天、第三天和最后一天测定血清中铁的浓度以及血清结合铁的潜在能力。接下来，计算铁的总结合能力和血浆转铁蛋白与铁的饱和度系数。在药物中毒的情况下，中毒后第二天和第三天血清中铁浓度有统计学意义的下降，而在住院的前三天其他测试参数未发现统计学意义的差异。在乙二醇中毒中，铁平衡的测试参数与药物中毒中的相似。在用PER、TRI和TETRA等溶剂中毒的情况下，铁浓度显著增加。
