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青蛙骨骼肌中的咖啡因挛缩和碘乙酸盐强直。一项比较。

Caffeine contracture and iodoacetate rigor in frog skeletal muscle. A comparison.

作者信息

Schwarz R P, Hsieh R, Johnson W H

出版信息

Biophys J. 1978 Jun;22(3):501-6. doi: 10.1016/S0006-3495(78)85502-7.

DOI:10.1016/S0006-3495(78)85502-7
PMID:667298
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1473479/
Abstract

Frog sartorius muscle treated with 5.0 mM or greater caffeine exhibits stiffness similar to that obtained from muscle in iodoacetate rigor. The data provide quantitative evidence that suggests that caffeine at irreversible contracture-producing concentrations somehow induces a rigor or rigorlike state in skeletal muscle.

摘要

用5.0毫摩尔或更高浓度咖啡因处理的青蛙缝匠肌表现出的僵硬程度与碘乙酸盐致僵肌肉相似。这些数据提供了定量证据,表明在产生不可逆挛缩的浓度下,咖啡因以某种方式在骨骼肌中诱导出一种僵硬或类似僵硬的状态。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d174/1473479/095f4c1a8708/biophysj00746-0157-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d174/1473479/6ff762109cd7/biophysj00746-0156-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d174/1473479/095f4c1a8708/biophysj00746-0157-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d174/1473479/6ff762109cd7/biophysj00746-0156-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d174/1473479/095f4c1a8708/biophysj00746-0157-a.jpg

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本文引用的文献

1
Activation of the contractile mechanism in striated muscle.横纹肌收缩机制的激活。
Acta Physiol Scand. 1958 Oct 28;44(1):55-66. doi: 10.1111/j.1748-1716.1958.tb01608.x.
2
The effect of nitrate on the active state of muscle.硝酸盐对肌肉活性状态的影响。
J Physiol. 1954 Oct 28;126(1):155-68. doi: 10.1113/jphysiol.1954.sp005200.
3
Caffeine- and potassium-induced contractures of frog striated muscle fibers in hypertonic solutions.高渗溶液中咖啡因和钾诱导的青蛙横纹肌纤维挛缩
J Gen Physiol. 1966 Sep;50(1):129-39. doi: 10.1085/jgp.50.1.129.
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Correlations of ATP content with mechanical properties of metabolically inhibited muscle.代谢抑制肌肉中ATP含量与力学性能的相关性
Am J Physiol. 1966 Nov;211(5):1082-8. doi: 10.1152/ajplegacy.1966.211.5.1082.
5
The relationship between caffeine contracture of intact muscle and the effect of caffeine on reticulum.完整肌肉的咖啡因挛缩与咖啡因对肌浆网的作用之间的关系
J Gen Physiol. 1968 Nov;52(5):750-9. doi: 10.1085/jgp.52.5.750.
6
Caffeine contracture of frog skeletal muscle and of single muscle fibers.青蛙骨骼肌和单根肌纤维的咖啡因挛缩
Am J Physiol. 1968 Aug;215(2):296-8. doi: 10.1152/ajplegacy.1968.215.2.296.
7
Caffeine contracture in muscle with disrupted transverse tubules.
Am J Physiol. 1971 Mar;220(3):712-7. doi: 10.1152/ajplegacy.1971.220.3.712.
8
Mitochondria and calcium ion transport.线粒体与钙离子运输
Biochem J. 1970 Sep;119(2):129-38. doi: 10.1042/bj1190129.
9
Effects of caffeine on the intracellular distribution of calcium in frog sartorius muscle.咖啡因对青蛙缝匠肌细胞内钙分布的影响。
J Cell Physiol. 1971 Dec;78(3):387-404. doi: 10.1002/jcp.1040780308.
10
Elastic modulus and stress relationships in stretched and shortened frog sartorii.拉伸和缩短的青蛙缝匠肌中的弹性模量与应力关系
Am J Physiol. 1976 Jan;230(1):205-10. doi: 10.1152/ajplegacy.1976.230.1.205.