Khadzhipetrov N, Georgiev S
Vutr Boles. 1983;22(5):86-9.
Thirty patients with chronic obstructive pulmonary disease (ChOPD) and concomitant ischemic heart disease (IHD) were studied that were admitted to the clinic for the treatment of a recurrence of the basic disease within the period 1981-1982. The patients were grouped into three groups of 10 patients and each group was treated for a period of 14 days, as follows: group 1--10 patients were given only sectral 50 mg per os during the first week and 10 mg/day during the second week; group II--treated with falicard, 5 mg daily, intravenously, for one week and later 2 X 5 mg, intravenously--the second week; group III, received sectral--50-100 mg/day after 5 mg falicard intravenously. Best results, manifested with a reduction of the paroxysms of dyspnea and stenocardia, were obtained in group III, suggesting the advantage of the combined effect with cardioselective beta-blockers and Ca-antagonists in the patients with ChOPD and concomitant IHD.
对30例患有慢性阻塞性肺疾病(ChOPD)并伴有缺血性心脏病(IHD)的患者进行了研究,这些患者于1981年至1982年期间因基础疾病复发入院治疗。将患者分为三组,每组10例,每组治疗14天,具体如下:第一组——10例患者在第一周口服心得舒50毫克,第二周每天10毫克;第二组——静脉注射速溶心痛定,每天5毫克,持续一周,之后第二周静脉注射2×5毫克;第三组——静脉注射5毫克速溶心痛定后,口服心得舒,每天50 - 100毫克。第三组取得了最佳效果,表现为呼吸困难和心绞痛发作次数减少,这表明在患有ChOPD并伴有IHD的患者中,心脏选择性β受体阻滞剂和钙拮抗剂联合使用具有优势。