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[地塞米松抑制试验与自杀]

[Dexamethasone suppression test and suicide].

作者信息

Van Wettere J P, Charles G, Wilmotte J

出版信息

Acta Psychiatr Belg. 1983;83(6):569-78.

PMID:6673520
Abstract

Suicidal behavior may be related to perturbations of the hypothalamo-pituitary axis. We administered the DST to 51 patients admitted for suicide attempt on admission day. No correlation is found between DST result and type of suicide attempt. The DST's diagnostic predictive value was absent for our population. Neither alcoholism, nor repeat of suicide attempt, nor suicidal behavior rating scales were correlated with DST results. Drug interference effects and the "stress" factor may explain our DST results on a population of suicide attemptors.

摘要

自杀行为可能与下丘脑 - 垂体轴的紊乱有关。我们在51例入院当天因自杀未遂入院的患者中进行了地塞米松抑制试验(DST)。未发现DST结果与自杀未遂类型之间存在相关性。对于我们的研究人群,DST没有诊断预测价值。酗酒、自杀未遂的复发以及自杀行为评定量表均与DST结果无关。药物干扰效应和“应激”因素可能解释了我们在自杀未遂人群中得到的DST结果。

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