Boivin G, Morel G, Meunier P J, Dubois P M
Biol Cell. 1983;49(3):227-30. doi: 10.1111/j.1768-322x.1984.tb00241.x.
Using transmission electron microscopy after cryoultramicrotomy, mineralized as well as unmineralized bone tissues and sutural cartilage were observed in neonatal mice calvaria. A good definition of osteoblasts (nucleus, membranes, organelles) and extracellular constituents (collagen fibrils, matrix vesicles, mineral substance) was obtained. The sutural zone was composed of an unmineralized cartilaginous tissue with more or less hypertrophic cells surrounded by a finely fibrillar matrix.
在冷冻超薄切片后使用透射电子显微镜观察新生小鼠颅骨中的矿化和未矿化骨组织以及缝合软骨。可以清晰地分辨出成骨细胞(细胞核、细胞膜、细胞器)和细胞外成分(胶原纤维、基质小泡、矿物质)。缝合区由未矿化的软骨组织组成,有或多或少的肥大细胞,周围是细纤维状基质。