Crippa L, Gilardi S, Assimacopoulos A, Engel E
J Genet Hum. 1983 Dec;31 Suppl 5:377-84.
An analysis of the sister chromatid exchanges has been carried out in lymphocytes from patients suffering from a severe form of psoriasis--pustular psoriasis (von Zumbusch), eruptive psoriasis vulgaris (more than 30% of the skin surface), severe arthropathic psoriasis and psoriatic erythroderma. These patients had never received treatment for their disorder. Our results, which show a normal level of sister chromatid exchanges in their blood cells, argue against the presence of a mutagenic factor in such patients.
对患有严重形式银屑病（脓疱型银屑病（冯·祖姆布施型）、泛发性脓疱型银屑病（皮肤表面超过30%受累）、重度关节病型银屑病和红皮病型银屑病）患者的淋巴细胞进行了姐妹染色单体交换分析。这些患者从未因自身疾病接受过治疗。我们的结果显示其血细胞中姐妹染色单体交换水平正常，这与这类患者中存在诱变因素的观点相悖。
