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[非血液预充体外循环后的肾功能]

[Renal function after non-blood priming extracorporeal circulation].

作者信息

Konno O

出版信息

Nihon Geka Gakkai Zasshi. 1983 Jan;84(1):20-30.

PMID:6674762
Abstract

Non-blood priming extracorporeal circulation (ECC) in open heart surgery was studied to evaluate its effect on kidney, and was compared with blood-priming ECC. Non-blood priming ECC was performed in 49 cases, and blood-priming ECC was performed in 25 cases. Serum creatinine creatinine clearance, BUN, UUN/BUN and urinary Na/K ratio were measured. Perfusion flow, total peripheral vascular resistance (TPR) and cardiac index after ECC were measured to know if there is a significant difference between the two groups. The following results were obtained: There were no significant differences between the two groups as to the perfusion flow, TPR during ECC and cardiac index after ECC. Using non-blood priming ECC was found to be the safer method from the point of preserving the renal function. When compared with blood priming ECC, the non-blood priming ECC was found to be more beneficial for the renal function. Renal failure was observed in 3 pediatric cases using blood priming ECC and 1 adult case using non-blood priming ECC. Low cardiac output syndrome or heart failure were thought to be causes of the renal failure in these 4 patients.

摘要

研究了心脏直视手术中无血预充体外循环(ECC)对肾脏的影响,并与血预充ECC进行了比较。49例患者采用无血预充ECC,25例患者采用血预充ECC。测量血清肌酐、肌酐清除率、血尿素氮、尿尿素氮/血尿素氮和尿钠/钾比值。测量ECC后的灌注流量、总外周血管阻力(TPR)和心脏指数,以了解两组之间是否存在显著差异。结果如下:两组在ECC期间的灌注流量、TPR和ECC后的心脏指数方面无显著差异。从保护肾功能的角度来看,使用无血预充ECC是更安全的方法。与血预充ECC相比,无血预充ECC对肾功能更有益。3例小儿患者采用血预充ECC发生肾衰竭,1例成人患者采用无血预充ECC发生肾衰竭。这4例患者的肾衰竭原因被认为是低心排血量综合征或心力衰竭。

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