Einarsson K, Björkhem I, Eklöf R, Blomstrand R
Scand J Gastroenterol. 1983 Jan;18(1):9-12. doi: 10.3109/00365528309181550.
The 14C-triolein breath test was evaluated as a screening test for fat malabsorption in 50 consecutive patients. After the ingestion of a 30-g fat meal containing 5 microCi 14C-triolein, the breath excretion of 14CO2 was measured at hourly intervals for 6 h and compared with a 3-day faecal excretion of fat. Nineteen patients had steatorrhoea and 31 patients normal fat excretion. The maximum specific activity of CO2 in the breath provided the best means of distinguishing between the two groups, with no false-negative values and nine false-positive values (29%). Our findings confirm that the 14C-triolein breath test is sensitive and has sufficient specificity for screening fat malabsorption, especially among outpatients. If a normal 14C-triolein breath test is obtained, it seems unnecessary to perform measurements of excretion of faecal fat.
对连续50例患者进行了¹⁴C-三油酸甘油酯呼气试验，以评估其作为脂肪吸收不良筛查试验的效果。摄入含有5微居里¹⁴C-三油酸甘油酯的30克脂肪餐后，每小时测量¹⁴CO₂的呼气排泄量，持续6小时，并与3天的粪便脂肪排泄量进行比较。19例患者有脂肪泻，31例患者脂肪排泄正常。呼气中CO₂的最大比活性是区分两组的最佳方法，无假阴性值，有9例假阳性值（29%）。我们的研究结果证实，¹⁴C-三油酸甘油酯呼气试验对筛查脂肪吸收不良敏感且具有足够的特异性，尤其是在门诊患者中。如果¹⁴C-三油酸甘油酯呼气试验结果正常，似乎没有必要进行粪便脂肪排泄量的测量。
