Hruban V, Dvorák P, Hradecký J, Pazdera J, Müller J
Anim Blood Groups Biochem Genet. 1983;14(4):299-304. doi: 10.1111/j.1365-2052.1983.tb01088.x.
Two cell membrane leucocyte alloantigens were detected in pigs by simple direct agglutination tests. Family studies showed that the locus controlling these antigens was not identical, or in close linkage, with the SLA major histocompatibility complex, SLB leucocyte locus or with the A, E, and N blood group loci. In the studied population, the locus termed SLC (Swine Leucocyte C locus) has two alleles controlling mutually exclusive antigens SLC-1 and SLC-2. The frequency of SLC1 and SLC2 alleles is 0.10 and 0.90, respectively. The antigens have not been detected on erythrocytes and thrombocytes but are well determined on granulocytes, peritoneal macrophages, mononuclears from different sources (thymus, spleen, bone marrow, lymph nodes) and enriched T and B cells from peripheral blood.
通过简单的直接凝集试验在猪中检测到两种细胞膜白细胞同种异体抗原。家系研究表明,控制这些抗原的基因座与猪主要组织相容性复合体(SLA)、SLB白细胞基因座或A、E和N血型基因座不相同,也没有紧密连锁。在所研究的群体中,称为SLC(猪白细胞C基因座)的基因座有两个等位基因,分别控制相互排斥的抗原SLC-1和SLC-2。SLC1和SLC2等位基因的频率分别为0.10和0.90。在红细胞和血小板上未检测到这些抗原,但在粒细胞、腹腔巨噬细胞、来自不同来源(胸腺、脾脏、骨髓、淋巴结)的单核细胞以及外周血中富集的T细胞和B细胞上可以很好地鉴定出来。