Maehle B O, Skjaerven R
Diagn Histopathol. 1983 Jul-Dec;6(3-4):221-8.
Statistical evaluation of the prognostic impact of different variants of the mean nuclear area (MNA) of tumour cells in breast carcinoma was used to find an optimal combination for use in conjunction with the absence/presence of tumour cells in the efferent vessels of the axillary nodes (EVI). This model gives an estimate of the relative prognostic impact of the different variables and their reliability. Combination of EVI with MNA of the primary tumour gave the optimal prediction of disease outcome; 81 per cent correct prediction before 60 months, falling to 73 per cent by 98 months after the operation.
对乳腺癌肿瘤细胞核平均面积（MNA）不同变体的预后影响进行统计学评估，以找到与腋窝淋巴结输出血管中有无肿瘤细胞（EVI）相结合使用的最佳组合。该模型给出了不同变量的相对预后影响及其可靠性的估计。EVI与原发肿瘤的MNA相结合能对疾病结局做出最佳预测；术后60个月前预测正确率为81%，到98个月时降至73%。
