Itho H, Kawamura J, Yoshida O, Tamaki N, Sakahara H, Mukai T, Yamamoto K, Fujita T, Torizuka K
Hinyokika Kiyo. 1983 Nov;29(11):1451-62.
Renal scintigraphy and regional renography using I-123- orthoiodohippurate were performed in 26 cases of obstructive nephropathy. After 1 mCi of I-123- orthoiodohippurate was given intravenously, serial renal scintigrams were obtained for 25 minutes and regional renogram curves were derived from the whole kidney, the cortical and pelvic areas. At the same time, renal functional images with Tmax as the peak arrival time were processed. Tmax in normal cases ranged from 2 to 3 minutes in the cortex and from 4 to 5 minutes in the pelvis, while there was some delay in Tmax in the obstructive nephropathy. In the case of acute ureteral obstruction by stones, most of the regional renograms in the cortex and pelvis improved soon after the removal of the obstruction. On the contrary, in the case of chronic obstructive nephropathy obstructive patterns on renogram curves was usually observed postoperatively. However, in some cases, functional images in cortical and/or pelvic areas showed marked recovery before improvement of findings on renograms or IVP. I-123- orthoiodohippurate renoscintigraphy is a useful adjunct for assessing pre- and post-operative renal function in obstructive nephropathy. Particularly, the analysis of regional renogram curves enables early prediction of postoperative recovery, and the functional image enables early detection of the functional recovery of the hydronephrotic kidney.
对26例梗阻性肾病患者进行了使用I-123-邻碘马尿酸的肾闪烁扫描和局部肾图检查。静脉注射1毫居里的I-123-邻碘马尿酸后，连续25分钟获取肾闪烁扫描图像，并从整个肾脏、皮质和肾盂区域得出局部肾图曲线。同时，处理以Tmax作为峰值到达时间的肾功能图像。正常情况下，皮质的Tmax为2至3分钟，肾盂的Tmax为4至5分钟，而梗阻性肾病患者的Tmax会有一些延迟。在结石导致急性输尿管梗阻的情况下，梗阻解除后，皮质和肾盂的大多数局部肾图很快改善。相反，在慢性梗阻性肾病患者中，术后肾图曲线通常会出现梗阻模式。然而，在某些情况下，皮质和/或肾盂区域的功能图像在肾图或静脉肾盂造影检查结果改善之前就显示出明显恢复。I-123-邻碘马尿酸肾闪烁扫描是评估梗阻性肾病术前和术后肾功能的有用辅助手段。特别是，对局部肾图曲线的分析能够早期预测术后恢复情况，而功能图像能够早期检测肾积水肾脏的功能恢复。
