Greene H J
Ann Rech Vet. 1983;14(4):548-55.
Calf morbidity and mortality rates up to three weeks old were 11.3% and 1.2% respectively when good husbandry was practised compared with 36.6% and 5.4% with poor husbandry. The annual mortality rate was 4% in earlier years when management was inadequate. The main features of good husbandry were feeding at least 2.25 litres of colostrum to each calf within the first hour of life to boost its immunity while minimising infection rates by regular thorough cleaning and disinfection of calving boxes and calf pens and providing uncrowded, dry, draught free accommodation. By these means satisfactory control of early calf losses was achieved without concentrating on specific microorganisms. Detailed examinations of sacrificed moribund diarrhoeic calves showed that E. coli, cryptosporidia, rota and corona viruses were associated agents. The serum immunoglobulin level of any individual calf was an unreliable guide to its future viability because 12 out of 488 calves with high levels died whereas 53 with unacceptably low levels remained healthy. Nevertheless when calves were grouped by immunoglobulin status the highest mortality rates occurred among those with low levels. Clinical examination of diarrhoeic calves to determine the degree of dehydration was more reliable than clinical pathologic laboratory tests. Results of a treatment trial indicated that oral glucose-glycine electrolyte solution alone was as beneficial as the electrolyte plus an oral triple sulphonamide and streptomycin. This was not unexpected in view of the widespread antibiotic resistance also demonstrated.
在采用良好饲养管理措施时,三周龄内犊牛的发病率和死亡率分别为11.3%和1.2%,而饲养管理差时则分别为36.6%和5.4%。早年管理不当时,年死亡率为4%。良好饲养管理的主要特点包括:在犊牛出生后第一小时内给每头犊牛至少喂2.25升初乳以增强其免疫力,同时通过定期彻底清洁和消毒产犊箱及犊牛栏,并提供不拥挤、干燥、无通风的环境,将感染率降至最低。通过这些方法,在不专注于特定微生物的情况下,实现了对早期犊牛损失的满意控制。对死亡濒死腹泻犊牛的详细检查表明,大肠杆菌、隐孢子虫、轮状病毒和冠状病毒是相关病原体。任何一头犊牛的血清免疫球蛋白水平都不能可靠地指导其未来的生存能力,因为488头免疫球蛋白水平高的犊牛中有12头死亡,而53头免疫球蛋白水平低得不可接受的犊牛却保持健康。然而,当按免疫球蛋白状态对犊牛进行分组时,死亡率最高的是免疫球蛋白水平低的犊牛。对腹泻犊牛进行临床检查以确定脱水程度比临床病理实验室检查更可靠。一项治疗试验的结果表明,单独使用口服葡萄糖 - 甘氨酸电解质溶液与使用电解质加口服三联磺胺和链霉素一样有益。鉴于也已证明的广泛抗生素耐药性,这并不意外。