Bohman S O, Jensen P K
Cell Tissue Res. 1978 May 18;189(1):1-18. doi: 10.1007/BF00223117.
The inner zone of the renal medulla of rats, gerbils, and rabbits was investigated to determine whether or not there are any characteristic ultrastructural differences between the interstitial cells of these species. The effects on the interstitial cells of water deprivation and water loading were also investigated. In all three species, the Type 1 interstitial cells, the lipid containing cells, were abundant and their distribution and topographical relations as well as their general ultrastructure were similar. The previously reported significantly higher frequency in desert rats could not be confirmed. Although the lipid droplets of the interstitial cells were smaller in gerbils and rabbits when compared to rats, their fine structure was similar. Their electron dense outer zone was sometimes associated with a granular material and/or a lamellar material with a periodicity of about 40 A resembling phospholipid "myelin figures". Water-loaded rats showed a considerable increase in the number of lipid droplets when compared to dehydrated or untreated animals. In contrast, the interstitial cells of waterloaded gerbils and rabbits were depleted of lipid droplets.
对大鼠、沙鼠和兔子肾髓质的内区进行了研究，以确定这些物种的间质细胞之间是否存在任何特征性的超微结构差异。还研究了缺水和水负荷对间质细胞的影响。在所有这三个物种中，1型间质细胞，即含脂质细胞，数量丰富，其分布、拓扑关系以及一般超微结构相似。先前报道的沙漠大鼠中明显更高的频率无法得到证实。尽管与大鼠相比，沙鼠和兔子间质细胞的脂滴较小，但其精细结构相似。它们电子密度高的外层区域有时与颗粒物质和/或具有约40埃周期的层状物质相关，类似于磷脂“髓鞘样结构”。与脱水或未处理的动物相比，水负荷大鼠的脂滴数量显著增加。相比之下，水负荷沙鼠和兔子的间质细胞脂滴减少。
