癌症患者红细胞己糖激酶与红细胞年龄之间的关系。

Relationship between erythrocyte hexokinase in cancer patients and red cell age.

作者信息

Canestrari F, Dachà U, Giacchi R, Magnani M, Stocchi V, Palma F, Piacentini G, Dachà M

出版信息

Tumori. 1983 Apr 30;69(2):89-93. doi: 10.1177/030089168306900202.

Abstract

A study of hexokinase isozymic pattern and age dependence of the enzyme was carried out on erythrocytes of 4 patients with adenocarcinoma of the gastrointestinal tract. On the basis of our results, we think that the increase in hexokinase activity previously reported and the increase in both subtypes (Ia and Ib) of the enzyme herein described are not due to a mean younger red cell population caused by secondary anemia, which is frequently present in cancer patients.

摘要

对4例胃肠道腺癌患者的红细胞进行了己糖激酶同工酶模式及该酶年龄依赖性的研究。根据我们的研究结果，我们认为先前报道的己糖激酶活性增加以及本文所述的该酶两种亚型（Ia和Ib）的增加并非由于继发性贫血导致的红细胞群体平均年龄较小，继发性贫血在癌症患者中很常见。