Warnick C T, Lazarus H M
Circ Shock. 1978;5(2):157-61.
Hemorrhagic shock causes an increase in the template activity of chromatin isolated from rat liver, as measured with E. coli RNA polymerase. The increase in template activity is directly related to the time of shock: The longer the shock period, the greater the increase in template activity. Reinfusion reduces the increased template activity. The increased template activity of the chromatin during hemorrhagic shock may be indicative of nuclear changes which contribute to the inability of the cell to recover from severe shock.
出血性休克会导致从大鼠肝脏分离出的染色质模板活性增加，这是用大肠杆菌RNA聚合酶测量得出的。模板活性的增加与休克时间直接相关：休克时间越长，模板活性增加得越多。再灌注会降低增加的模板活性。出血性休克期间染色质模板活性的增加可能表明存在核变化，这些变化导致细胞无法从严重休克中恢复。
