Tinozzi S, Valesi M G, Ferrari R
Chir Ital. 1983 Dec;35(6):843-50.
Among the more indicative complications encountered in gastrectomized patients, particularly in those cases where the Billroth II technique is used, bile and/or pancreatic reflux is undoubtedly one of the most important manifestations. The abolition of the "sphincteric" function of the pylorus creates a pathophysiological condition of the above-mentioned type when the surgery is not combined with specific antireflux techniques or when particular situations obtain which make alkaline reflux inevitable. These pathophysiological disorders lead to a "chronic gastritis of the stump", which often exhibits differing symptomatic pictures. There are patients in whom there is no correspondence between the anatomo-pathological and symptomatic pictures and who do not suffer at all, phereas there are others (5-35%) who complain of severe symptoms such as epigastric pain aggravated by ingestion of food, reduction in weight, nausea, bile vomiting and often haemorrhagic stillicide with consequent sideropaenic hypochromic anaemia. Taking the above-mentioned considerations as their starting point, the authors set out to investigate these complications more thoroughly in the pathology of gastrectomized patients by means of the long-term follow-up of such patients coming to them for observation after having been subjected to surgical therapy in the form of Billroth II gastric resection (gastro-enterostomy according to Balfour-Kroenlein, or according to Hofmeister-Fininsterer). The study, which is currently still in progress, involves a thorough clinical examination of the symptoms complained of as well as radiological, gastroscopic, histological and haematochemical investigations. The authors report on their preliminary results.
在接受胃切除手术的患者中,尤其是采用毕Ⅱ式手术的患者所出现的更具指示性的并发症中,胆汁和/或胰液反流无疑是最重要的表现之一。当手术未结合特定的抗反流技术,或者出现特定情况导致碱性反流不可避免时,幽门“括约肌”功能的丧失会造成上述类型的病理生理状况。这些病理生理紊乱会导致“残胃炎”,其症状表现往往各不相同。有些患者的解剖病理表现与症状不相符,且毫无痛苦,而另一些患者(5% - 35%)则主诉有严重症状,如进食后加重的上腹部疼痛、体重减轻、恶心、胆汁呕吐,以及常伴有出血性胃液反流,进而导致缺铁性低色素性贫血。基于上述考虑,作者通过对接受毕Ⅱ式胃切除术(按照巴尔弗 - 克伦莱因法或霍夫迈斯特 - 菲宁斯特勒法进行胃肠吻合术)后前来接受观察的患者进行长期随访,着手更深入地研究胃切除患者病理中的这些并发症。目前仍在进行的这项研究包括对患者所主诉症状进行全面的临床检查,以及进行放射学、胃镜检查、组织学和血液化学检查。作者报告了他们的初步结果。