Luukkainen R, Kaarela K, Isomäki H, Martio J, Kiviniemi P, Räsänen J, Sarna S
Clin Exp Rheumatol. 1983 Oct-Dec;1(4):295-8.
A total of 107 patients with definite rheumatoid arthritis of no longer than six months' duration were observed for three years. The radiological destruction of the hand and foot joints after the follow-up time was compared with 65 anamnestic, clinical, laboratory and radiological variables at the onset of the disease. Of the individual variables, early radiological changes in the joints showed the best correlation with the progress of joint destruction. Grip strength, ESR, serum iron, serum C1 esterase inhibitor, rheumatoid factor and old age also had prognostic value. In multiple regression analysis 15 variables explained about 50% of the variance in the progress of joint destruction.
共观察了107例病程不超过6个月的明确类风湿关节炎患者3年。将随访期后手和足关节的放射学破坏情况与疾病发作时的65项既往史、临床、实验室和放射学变量进行了比较。在各个变量中，关节早期放射学改变与关节破坏进展的相关性最佳。握力、血沉、血清铁、血清C1酯酶抑制剂、类风湿因子和高龄也具有预后价值。在多元回归分析中，15个变量解释了关节破坏进展中约50%的方差。
