Ogawa M, Kosaki G, Matsuura K, Fujimoto K I, Minamiura N, Yamamoto T, Kikuchi M
Clin Chim Acta. 1978 Jul 1;87(1):17-21. doi: 10.1016/0009-8981(78)90051-7.
The effects of peptidoglutaminase (PGln-ase) I and II on human pancreatic juice amylase purified as an isozyme were investigated. Several amylase isozymes were formed which corresponded to minor components of pancreatic amylase isozymes, indicating that appearance of amylase isozymes are due to enzymic deamidation. A similar result was observed when the purified amylase isozyme was incubated with the supernatant of human pancreatic juice whose amylase was previously removed by adsorption onto raw corn starch. These findings are discussed in connection with amylase isozymes in the sera of the patients suffering from pancreatic inflammation.
研究了肽谷氨酰胺酶（PGln - 酶）I和II对作为同工酶纯化的人胰液淀粉酶的影响。形成了几种淀粉酶同工酶，它们对应于胰腺淀粉酶同工酶的次要成分，这表明淀粉酶同工酶的出现是由于酶促脱酰胺作用。当将纯化的淀粉酶同工酶与先前通过吸附到生玉米淀粉上而去除淀粉酶的人胰液上清液一起孵育时，观察到了类似的结果。结合患有胰腺炎症患者血清中的淀粉酶同工酶对这些发现进行了讨论。
