Aigner K, Schwemmle K
Langenbecks Arch Chir. 1983;359(2):113-22. doi: 10.1007/BF01257258.
In 171 cases of isolated perfusion of the extremities for treatment of melanomas and soft tissue sarcomas, standardized operation techniques were perfected. The arterial double cannulation makes an iliac cannulation feasible also in cases of second and third perfusion. Cytostatics are dosed per liter of perfused extremity. Cis-Platinum and dacarbacine were recently introduced in isolation perfusion treatment. So-called preheating of the extremity before adding the drugs allows administration of cytostatics besides tumortoxic hyperthermia.
在171例采用肢体隔离灌注治疗黑色素瘤和软组织肉瘤的病例中，标准化手术技术得到了完善。动脉双插管使得在第二次和第三次灌注时也能进行髂动脉插管。细胞抑制剂按每升灌注肢体给药。顺铂和达卡巴嗪最近被引入隔离灌注治疗。在添加药物之前对肢体进行所谓的预热，除了肿瘤毒性高温外，还能进行细胞抑制剂的给药。
