Sommer H J
Urologe A. 1983 Jan;22(1):35-43.
The epididymal tissue and the testis biopsy from 30 patients with obstructive azoospermia, who had undergone refertilization operations, were investigated by light- and electron microscopy. The findings give an insight into the morphologically recognizable tissue relationships, which one finds in patients with congenital or acquired obstruction of the deferent duct. A severe blockage of the testicular secretion is found in the epithelium of these epididymal ducts and demonstrate considerable pathological tissue changes, which indicate an intense resorptive activity. Intra-luminal spermatophages, which are loaded with phagocytized spermatozoa fragments, penetrate through the epithelium. Also great numbers of monocytes, as well as mast cells, and lymphocytes appear in the interstitium. The autoimmune reaction, induced by the continual blockage of epididymal passage over a long period of time, is discussed.
对30例接受再生育手术的梗阻性无精子症患者的附睾组织和睾丸活检标本进行了光镜和电镜检查。这些发现揭示了在先天性或后天性输精管梗阻患者中可在形态学上识别的组织关系。在这些附睾管的上皮中发现了睾丸分泌物的严重阻塞，并显示出相当大的病理组织变化，这表明存在强烈的吸收活性。腔内充满吞噬的精子碎片的吞噬细胞穿透上皮。间质中也出现大量单核细胞、肥大细胞和淋巴细胞。讨论了长期附睾通道持续阻塞所引发的自身免疫反应。
