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羊体内黄体对氯前列醇的反应性消退不受子宫切除术后黄体催产素缺失的影响。

Regression of the corpora lutea in sheep in response to cloprostenol is not affected by loss of luteal oxytocin after hysterectomy.

作者信息

Sheldrick E L, Flint A P

出版信息

J Reprod Fertil. 1983 May;68(1):155-60. doi: 10.1530/jrf.0.0680155.

DOI:10.1530/jrf.0.0680155
PMID:6682444
Abstract

Concentrations of oxytocin in corpora lutea were reduced from 1706 to less than 15 ng/g wet wt after hysterectomy in sheep during the oestrous cycle. Hysterectomy also blocked the appearance of raised levels of oxytocin in ovarian and jugular venous plasma caused by cloprostenol. Administration of cloprostenol to hysterectomized ewes resulted in luteal regression, which occurred as rapidly as in intact animals. Therefore oxytocin in the corpus luteum during the oestrous cycle is unlikely to be involved in intraluteal events mediating prostaglandin-induced luteolysis.

摘要

在发情周期中,对绵羊进行子宫切除术后,黄体中催产素的浓度从1706 ng/g湿重降至不足15 ng/g湿重。子宫切除术还阻止了氯前列醇引起的卵巢和颈静脉血浆中催产素水平的升高。对子宫切除的母羊施用氯前列醇会导致黄体退化,其发生速度与完整动物一样快。因此,发情周期中黄体中的催产素不太可能参与介导前列腺素诱导的黄体溶解的黄体内部事件。

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J Reprod Fertil. 1983 May;68(1):155-60. doi: 10.1530/jrf.0.0680155.
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