Franzolin A, Matheus M, Ferrari I, Jorge S M, Sala M A
Z Geburtshilfe Perinatol. 1983 Jan-Feb;187(1):44-7.
Cytogenetic studies were carried out on 24 newborns with single umbilical artery (SUA), whereas dermatoglyphic analysis were performed on 14 of them. Metaphase examination showed increased size of the short arm of an acrocentric chromosome of group D or of group G in 6 of the 24 SUA babies studied. Numerous chromosome breaks were detected in one other case. Dermatologlyphic data showed that the total finger ridge count did not deviate from normal patterns, whereas the aTd angle showed increased values in 5 of the 14 cases studied. The absence of major chromosome aberrations does not exclude the possibility of chromosomal etiology for SUA, since the increased frequency of acrocentric polymorphism found in the present series and the 5 cases of increased aTd angle suggest such an occurrence.
对24例单脐动脉（SUA）新生儿进行了细胞遗传学研究，其中14例进行了皮纹分析。中期检查显示，在研究的24例SUA婴儿中，有6例D组或G组近端着丝粒染色体短臂大小增加。在另一例中检测到许多染色体断裂。皮纹数据显示，总指嵴数未偏离正常模式，而在研究的14例中有5例aTd角值增加。主要染色体畸变的缺失并不排除SUA存在染色体病因的可能性，因为本系列中发现的近端着丝粒多态性频率增加以及5例aTd角增加的病例提示了这种情况的发生。
