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口服锌补充剂对健康矮小儿童生长、激素水平及锌含量的影响

Effect of oral zinc supplements on growth, hormonal levels, and zinc in healthy short children.

作者信息

Ghavami-Maibodi S Z, Collipp P J, Castro-Magana M, Stewart C, Chen S Y

出版信息

Ann Nutr Metab. 1983;27(3):214-9. doi: 10.1159/000176660.

DOI:10.1159/000176660
PMID:6683093
Abstract

13 short children aged 7-13 years who had a retarded bone age and low hair zinc concentration (under 140 micrograms/g) were treated with oral zinc supplements for a year. There was a significant increase in the growth rate in the children whose hair zinc concentration increased. Growth hormone, testosterone and somatomedin C also increased after oral zinc supplementation. Data from 755 short healthy children who have attended our Growth Clinic are presented which describe their hair and serum zinc concentration at different ages. The data indicate a decline in hair zinc concentration after birth with a gradual increase at age 4-6 years, finally reaching adult normal levels after adolescence.

摘要

13名年龄在7至13岁之间、骨龄发育迟缓且头发锌浓度较低(低于140微克/克)的矮小儿童接受了为期一年的口服锌补充剂治疗。头发锌浓度增加的儿童生长速率显著提高。口服锌补充剂后,生长激素、睾酮和生长调节素C也有所增加。本文展示了755名曾就诊于我们生长诊所的健康矮小儿童的数据,这些数据描述了他们在不同年龄的头发和血清锌浓度。数据表明,出生后头发锌浓度下降,在4至6岁时逐渐上升,青春期后最终达到成人正常水平。

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Effect of oral zinc supplements on growth, hormonal levels, and zinc in healthy short children.口服锌补充剂对健康矮小儿童生长、激素水平及锌含量的影响
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