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[异时胸腺移植对CBA小鼠免疫反应性发育的影响。2. 移植到未受损伤的动物体内]

[Effect of the transplantation of heterochronic thymus on the development of immunological reactivity in CBA mice. 2. Transplantation to intact animals].

作者信息

Kharazi A I, Butenko G M

出版信息

Ontogenez. 1983;14(3):328-31.

PMID:6683830
Abstract

The effect of transplantation of thymus from donors of different age on the immune system development was studied in the newborn CBA mice. The thymuses of 22 month and 5 day old donors were shown to exert different effects: accelerated (early attainment of the plateau) and decelerated (late attainment of the peak) maturation of the immune system in the recipients. This fact is discussed with respect to interaction of transplanted and host thymuses.

摘要

在新生CBA小鼠中研究了不同年龄供体的胸腺移植对免疫系统发育的影响。结果显示,22月龄和5日龄供体的胸腺产生了不同的影响:受体免疫系统成熟加速(较早达到平台期)和减速(较晚达到峰值)。针对移植胸腺与宿主胸腺的相互作用对这一事实进行了讨论。

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