Shirai T, Tomino Y, Sato M, Yoshiki T, Itoh T
Contrib Nephrol. 1978;9:88-100. doi: 10.1159/000401436.
In a total of 283 biopsies, 100 (35%) were found to be IgA nephropathy. The incidence reached 40% among primary glomerulonephropathies. On the basis of histopathologic changes in glomeruli, these biopsies were classified into 3 groups. The criteria employed correlated well with clinical, laboratory and immunofluorescent findings. Immune complex pathogenesis was discussed in relation to our findings.
在总共283例活检中,发现100例(35%)为IgA肾病。在原发性肾小球疾病中,其发病率达40%。根据肾小球的组织病理学变化,这些活检被分为3组。所采用的标准与临床、实验室及免疫荧光检查结果密切相关。结合我们的研究结果对免疫复合物发病机制进行了讨论。