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Acta Otorhinolaryngol Belg. 1983;37(1):44-56.
Chronic otitis media with effusion ('secretory') is one of the most common diseases of childhood. Pathogenesis related to Eustachian tube dysfunction. Bacteria have been isolated from approximately 50 percent of chronic middle ear effusions. Diagnosis by pneumatic otoscopy or tympanometry, or both. Efficacy yet to be shown for antimicrobial therapy, decongestants, antihistamines, hydrocortisone, myringotomy with or without tympanostomy tubes, and adenoidectomy with or without tonsillectomy. However, a 10-day trial with an antimicrobial agent, such as amoxicillin (erythromycin and sulfonamide, trimethoprim-sulfamethoxazole, or cefaclor, are reasonable alternatives), should be prescribed before surgical intervention. Attendant conductive hearing loss may be related to abnormalities in cognition, language, and learning. Since the prevalence and incidence of otitis media decrease with advancing age, palliative management options would appear to be appropriate at present, reserving the more aggressive options for those infants and children who have frequently recurrent or chronic disease or the complications or sequelae of otitis media with effusion.
分泌性中耳炎是儿童期最常见的疾病之一。其发病机制与咽鼓管功能障碍有关。约50%的慢性中耳积液中可分离出细菌。通过鼓气耳镜检查或鼓室图检查,或两者结合进行诊断。抗菌治疗、减充血剂、抗组胺药、氢化可的松、鼓膜切开术(伴或不伴鼓膜置管)以及腺样体切除术(伴或不伴扁桃体切除术)的疗效尚未得到证实。然而,在手术干预前,应先进行为期10天的抗菌药物试验,如阿莫西林(红霉素、磺胺类药物、甲氧苄啶-磺胺甲恶唑或头孢克洛是合理的替代药物)。伴随的传导性听力损失可能与认知、语言和学习方面的异常有关。由于中耳炎的患病率和发病率随年龄增长而降低,目前姑息性治疗方案似乎是合适的,对于那些患有频繁复发或慢性疾病或分泌性中耳炎并发症或后遗症的婴幼儿和儿童,则保留更积极的治疗方案。