Tenenbaum D G, Piasecki G J, Oh W, Rosenkrantz T S, Jackson B T
Am J Obstet Gynecol. 1983 Sep 1;147(1):48-51. doi: 10.1016/0002-9378(83)90082-0.
To evaluate the effect of fetal polycythemia and hyperviscosity on fetal oxygen transport, we induced those conditions in eight chronically instrumented fetal lambs by isovolemic exchange transfusion with packed red cells obtained from a donor ewe. This procedure resulted in polycythemia and hyperviscosity without altering fetal arterial blood oxygen content. The fetuses were studied at 1 and 48 hours after polycythemia and hyperviscosity. In spite of decreased oxygen delivery to the fetus, the fetal oxygen consumption was unchanged because of an increase in oxygen extraction by the fetus.
为评估胎儿红细胞增多症和高黏滞血症对胎儿氧转运的影响，我们通过用从供体母羊获取的浓缩红细胞进行等容交换输血，在八只长期植入监测仪器的胎羊中诱发了这些情况。该操作导致了红细胞增多症和高黏滞血症，而未改变胎儿动脉血氧含量。在红细胞增多症和高黏滞血症发生后的1小时和48小时对胎儿进行了研究。尽管胎儿的氧输送减少，但由于胎儿氧摄取增加，胎儿的氧消耗并未改变。
