Foltyn P, Lücker P W, Schnitker J, Wetzelsberger N
Arzneimittelforschung. 1983;33(6):865-7.
1-Anisoyl-2-pyrrolidinone (aniracetam, Ro 13-5057) belongs to the group of cyclic GABA-derivatives. The compound showed a protective effect on the central nervous system in animal experiments. This paper reports on a clinical investigation in 60 patients of a geriatric and nursing home. The resocializing and the revitalizing effect were the observed parameters. The criteria were recorded by the physician and the staff. The results show that the evaluations by physicians and nursing staff were in good accordance. Aniracetam was effective with respect to the indication: cerebrovascular insufficiency.
1-茴酰基-2-吡咯烷酮(阿尼西坦,Ro 13-5057)属于环状γ-氨基丁酸衍生物类。该化合物在动物实验中显示出对中枢神经系统的保护作用。本文报道了对一家老年疗养院60名患者的临床研究。观察参数为重新社交化和恢复活力的效果。标准由医生和工作人员记录。结果表明,医生和护理人员的评估结果高度一致。阿尼西坦在脑血管功能不全这一适应症方面是有效的。