顺二氯二氨铂：一种具有耳毒性作用的细胞抑制剂。
cis-Diamminedichloroplatinum: a cytostatic with an ototoxic effect.
作者信息
Hartwig S, Pettersson U, Stahle J
出版信息
ORL J Otorhinolaryngol Relat Spec. 1983;45(5):257-61. doi: 10.1159/000275652.
PMID:6684750
Abstract
Among 74 patients treated with cis-diamminedichloroplatinum in total doses of 130-590 mg/m2 body surface area, high tone hearing loss was observed in 3. The caloric and rotatory responses were reduced in 3 other patients. Optokinetic responses remained normal in all patients.
摘要
在74例接受顺二氨二氯铂治疗、总剂量为130 - 590毫克/平方米体表面积的患者中，有3例出现了高调听力丧失。另外3例患者的冷热试验和旋转试验反应减弱。所有患者的视动试验反应均保持正常。
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