Meglioli-Bornand G
Rev Esp Fisiol. 1983 Jun;39(2):117-22.
The quantity of physiological uterine fluid secreted by rats exhibiting a regular four-day sexual cycle was measured at every stage and the freshly ovulated rat ova, surrounded by their cumulus cells, were incubated at 37 degrees C in this secretion sample. The results showed that the fluid began to be secreted on the morning of vaginal pro-oestrus and increased steadily for about 24 h. Two declines in quantity are observed, a slight one at the end of pro-oestrus and a marked one about 4 hours after the start of vaginal oestrus which coincided with ovulation. No secretion is obtained either at metaoestrus or at dioestrus. Only the secretion at the oestrus stages caused total dispersion of the corona cells in vitro. This property is retained after freezing, heating to 60 degrees C and lyophilization. A correlation with plasma sexual hormone measurement and some fertility factor contained in uterine secretion was discussed in relation to this dispersing activity.
对处于规律的四天性周期的大鼠分泌的生理性子宫液量在每个阶段进行了测量，并将刚排卵的、被卵丘细胞包围的大鼠卵子在37摄氏度下于该分泌样本中孵育。结果显示，该液体在阴道动情前期的早晨开始分泌，并持续稳定增加约24小时。观察到量有两次下降，一次在动情前期结束时轻微下降，另一次在阴道发情开始约4小时后显著下降，这与排卵时间一致。在间情期或动情后期均未获得分泌液。只有发情期阶段的分泌液能在体外使卵冠细胞完全分散。这种特性在冷冻、加热至60摄氏度和冻干后仍保留。针对这种分散活性，讨论了与血浆性激素测量以及子宫分泌中所含某些生育因子的相关性。
