Huber H, Kofler E, Müller G, Reinold E
Z Geburtshilfe Perinatol. 1983 Jul-Aug;187(4):175-7.
Plasma volume was measured with 131I-marked human albumin in 32 cases of gestosis at 35 to 38 weeks gestation. The same tests were made in 4 nonpregnant women. We examined 24 patients suffering from medium to severe gestosis (above 4 points according to Goecke) and 8 patients suffering from minimal gestosis (under 4 points). 4 nonpregnant women exhibited a mean plasma volume of 41.3 ml kg body weight, whereas patients suffering from minimal gestosis exhibited a mean plasma volume of 51.5 ml/kg body weight, in those suffering from medium to severe gestosis we found a volume of 48 ml/kg body weight. There was no significant correlation between the severity of the gestosis and plasma volume reduction, in contrast to birth weight of the infant with regard to gestation period and plasma volume. A low plasma volume in the mother was closely correlated to fetal dystrophy. The sensitivity of the method was 88.8%, specificity 80%.
采用131I标记的人血白蛋白对32例妊娠35至38周的妊娠中毒症患者进行血浆容量测定。对4名非妊娠妇女进行了同样的检测。我们检查了24例中重度妊娠中毒症患者(根据戈克评分高于4分)和8例轻度妊娠中毒症患者(低于4分)。4名非妊娠妇女的平均血浆容量为41.3毫升/千克体重,而轻度妊娠中毒症患者的平均血浆容量为51.5毫升/千克体重,中重度妊娠中毒症患者的血浆容量为48毫升/千克体重。与婴儿出生体重与妊娠期及血浆容量的关系不同,妊娠中毒症的严重程度与血浆容量减少之间无显著相关性。母亲血浆容量低与胎儿发育不良密切相关。该方法的敏感性为88.8%,特异性为80%。