Businco L, Marchetti F, Pellegrini G, Perlini R
Clin Allergy. 1983 Nov;13(6):503-8. doi: 10.1111/j.1365-2222.1983.tb02631.x.
Cord serum IgE levels were examined in 101 newborn infants of atopic parents, and reviewed at the ages of 3, 6, 9, 12, 15, 18, 21 and 24 months, in order to determine any relation with signs and symptoms of allergic rhinitis, bronchial asthma, atopic dermatitis, urticaria and food allergy. Cord blood IgE levels were 1.06 +/- 1.02 U/ml in the group of infants who developed atopic disease, and 0.34 +/- 0.79 U/ml in the group of infants who did not develop atopy (P less than 0.001). In the breast-fed group 37.5% of the infants with cord blood IgE more than 0.8 U/ml and 11.5% with IgE below 0.8 U/ml had atopic disease. In the soy-fed group 33.3% of the infants with cord blood IgE more than 0.8 U/ml and 15.8% with cord blood IgE less than 0.8 U/ml developed atopy. Ninety percent of the cow's milk-fed infants with cord blood IgE above 0.8 U/ml and 16% with cord blood IgE below 0.8 U/ml showed atopy during the follow-up period. No correlation was found between the IgE levels in maternal and respective cord blood.
对101名有特应性父母的新生儿的脐血免疫球蛋白E（IgE）水平进行了检测，并在其3、6、9、12、15、18、21和24个月大时进行复查，以确定其与过敏性鼻炎、支气管哮喘、特应性皮炎、荨麻疹和食物过敏的体征及症状之间的关系。患特应性疾病的婴儿组脐血IgE水平为1.06±1.02 U/ml，未患特应性疾病的婴儿组脐血IgE水平为0.34±0.79 U/ml（P<0.001）。在母乳喂养组中，脐血IgE高于0.8 U/ml的婴儿中有37.5%患特应性疾病，脐血IgE低于0.8 U/ml的婴儿中有11.5%患特应性疾病。在大豆喂养组中，脐血IgE高于0.8 U/ml的婴儿中有33.3%患特应性疾病，脐血IgE低于0.8 U/ml的婴儿中有15.8%患特应性疾病。在随访期间，脐血IgE高于0.8 U/ml的牛奶喂养婴儿中有90%患特应性疾病，脐血IgE低于0.8 U/ml的婴儿中有16%患特应性疾病。未发现母体和相应脐血中的IgE水平之间存在相关性。
