通过分子杂交对人凝血因子IX基因进行区域定位。
Regional localization of the human factor IX gene by molecular hybridization.
作者信息
Chance P F, Dyer K A, Kurachi K, Yoshitake S, Ropers H H, Wieacker P, Gartler S M
出版信息
Hum Genet. 1983;65(2):207-8. doi: 10.1007/BF00286666.
PMID:6686210
Abstract
A cloned cDNA probe encoding human factor IX was used for detecting homologous sequences in rodent human X chromosome hybrids and in human metaphase chromosome preparations. The results of these studies indicate that human factor IX is localized to the Xq27 leads to Xqter region.
摘要
一个编码人凝血因子IX的克隆cDNA探针被用于检测啮齿动物-人X染色体杂种细胞以及人中期染色体标本中的同源序列。这些研究结果表明，人凝血因子IX定位于Xq27至Xqter区域。
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