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人类、小牛、兔子和鸡血清中胆固醇与磷脂浓度之间的关系。

Relationships between cholesterol and phospholipid concentrations in the serum of humans, calves, rabbits and chickens.

作者信息

Beynen A C, Terpstra A H

出版信息

Comp Biochem Physiol B. 1983;76(4):737-40. doi: 10.1016/0305-0491(83)90386-3.

DOI:10.1016/0305-0491(83)90386-3
PMID:6686517
Abstract

In humans, calves and rabbits very strong correlations were found between the concentrations of serum total cholesterol and phospholipids; in these species more than 70% of the variance in the level of serum phospholipids is accounted for by the variance in the serum cholesterol concentration. The regression coefficients in the equations relating the concentration of serum cholesterol to that of phospholipids were almost identical in humans and rabbits, but differed from those observed in calves and chickens. It is suggested that the rabbit is a suitable model animal for studying the relation between cholesterol and phospholipids in human serum.

摘要

在人类、小牛和兔子中,发现血清总胆固醇浓度与磷脂浓度之间存在很强的相关性;在这些物种中,血清磷脂水平超过70%的变异可由血清胆固醇浓度的变异来解释。在人类和兔子中,将血清胆固醇浓度与磷脂浓度相关联的方程中的回归系数几乎相同,但与在小牛和鸡中观察到的回归系数不同。有人提出,兔子是研究人类血清中胆固醇与磷脂关系的合适模型动物。

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