Wicker P, Roudaut R, Haissaguere M, Villega-Arino P, Clementy J, Dallocchio M
Eur Heart J. 1983 Nov;4 Suppl G:1-5. doi: 10.1093/eurheartj/4.suppl_g.1.
To assess the prevalence of asymmetric septal hypertrophy (ASH) in hypertensive patients, 613 echocardiographic examinations performed over a period of one year were reviewed. Asymmetric septal hypertrophy (defined by an echocardiographic interventricular septum to left ventricular free wall thickness ratio of greater than or equal to 1.3 and by the presence of suggestive two-dimensional echocardiographic abnormalities) was found in 28 patients (5%). Clinical characteristics of asymmetric septal hypertrophy were assessed in 101 patients who underwent a complete evaluation. Patients with asymmetric septal hypertrophy (n = 9) were compared with patients with echocardiographic symmetrical left ventricle hypertrophy (n = 38) and without left ventricular hypertrophy (n = 54). Our results indicate that neither the severity of hypertension, nor the renin-angiotensin system nor sympathetic nerve activity appear to be the primary determinants in the development of asymmetric septal hypertrophy.
为评估高血压患者中不对称性室间隔肥厚（ASH）的患病率，回顾了在一年时间内进行的613次超声心动图检查。在28例患者（5%）中发现了不对称性室间隔肥厚（通过超声心动图测量的室间隔与左心室游离壁厚度之比大于或等于1.3以及存在二维超声心动图异常表现来定义）。对101例接受全面评估的患者的不对称性室间隔肥厚的临床特征进行了评估。将不对称性室间隔肥厚患者（n = 9）与超声心动图显示对称性左心室肥厚患者（n = 38）和无左心室肥厚患者（n = 54）进行了比较。我们的结果表明，高血压的严重程度、肾素 - 血管紧张素系统以及交感神经活动似乎均不是不对称性室间隔肥厚发生的主要决定因素。
