Poizat R, Goebel R, Kuss E
J Gynecol Obstet Biol Reprod (Paris). 1983;12(8):865-72.
It is possible to estimate the daily rate of oestriol production by the fetoplacental unit to monitor pregnancy by radio-immunoassay of the concentrations of unconjugated and total oestriol in the serum. The usefulness of these two parameters was compared by comparing variations from day to day in the same individuals and between them and other individuals, as well as over 24 hours. We think the best choice of test for biochemical monitoring of at-risk pregnancies is the estimation of unconjugated oestriol because there is a lower day to day variation in the same individual as well as throughout the 24 hours.
通过对血清中未结合雌三醇和总雌三醇浓度进行放射免疫测定,来估算胎儿胎盘单位每日雌三醇的生成率,以此监测妊娠情况是可行的。通过比较同一人群、不同人群之间以及24小时内每日的变化情况,对这两个参数的实用性进行了比较。我们认为,对于有风险妊娠的生化监测,最佳的检测选择是估算未结合雌三醇,因为同一人群在每日以及24小时内的变化较小。