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叶绿素铜钠盐对草酸钙晶体生长的抑制作用

Growth retardation of calcium oxalate by sodium copper chlorophyllin.

作者信息

Desjardins A, Tawashi R

出版信息

Eur Urol. 1978;4(4):294-7. doi: 10.1159/000473975.

DOI:10.1159/000473975
PMID:668744
Abstract

Earlier reports from our laboratories described the inhibitory effect of Mg++ and pyrophosphate on the dissolution and growth of calcium oxalate. In this report, growth of Ca oxalate in presence of very low concentration of chlorophyllin was followed by the Coulter counter and a multichannel analyser. The effect of chlorophyllin concentration on crystal formation was studied at different levels of supersaturation. A concentration of 0.1 microgram/ml produced a remarkable retardation of the induction period and the growth rate. The findings obtained in this study are discussed in the light of the crystal poisoning theory. Comparison was made between chlorophyllin and other growth inhibitors.

摘要

我们实验室早期的报告描述了镁离子和焦磷酸盐对草酸钙溶解和生长的抑制作用。在本报告中,使用库尔特计数器和多通道分析仪跟踪了在极低浓度叶绿酸存在下草酸钙的生长情况。在不同的过饱和水平下研究了叶绿酸浓度对晶体形成的影响。0.1微克/毫升的浓度显著延长了诱导期并降低了生长速率。根据晶体中毒理论对本研究获得的结果进行了讨论。对叶绿酸和其他生长抑制剂进行了比较。

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1
Growth retardation of calcium oxalate by sodium copper chlorophyllin.叶绿素铜钠盐对草酸钙晶体生长的抑制作用
Eur Urol. 1978;4(4):294-7. doi: 10.1159/000473975.
2
Growth retardation of weddellite (calcium oxalate dihydrate) by sodium copper chlorophyllin.叶绿素铜钠盐对水草酸钙(二水合草酸钙)生长的抑制作用
Invest Urol. 1980 Sep;18(2):86-9.
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Effect of sodium copper chlorophyllin on the formation of calcium oxalate crystals in rat kidney.叶绿酸铜钠对大鼠肾脏草酸钙晶体形成的影响。
Invest Urol. 1980 Sep;18(2):90-2.
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Crystallisation of calcium oxalate dihydrate in normal urine in presence of sodium copper chlorophyllin.在叶绿酸铜钠存在的情况下,正常尿液中草酸钙二水合物的结晶。
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[The quantitative study of inhibitory effect of pentosan polysulfate and chlorophyllin on the experimental calcium oxalate stone].[聚戊糖硫酸酯和叶绿酸对实验性草酸钙结石抑制作用的定量研究]
Nihon Hinyokika Gakkai Zasshi. 1989 Jun;80(6):861-9. doi: 10.5980/jpnjurol1989.80.861.
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[Inhibitory effect of sodium copper chlorophyllin on the formation, growth and aggregation of calcium oxalate crystals in vitro].
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[Studies of sodium pentosan polysulphate (SPP) therapy on the urinary stone disease. Experimental studies on the calcium oxalate crystallization and the effects in healthy subjects].[戊聚糖多硫酸钠(SPP)治疗尿路结石病的研究。草酸钙结晶的实验研究及对健康受试者的影响]
Nihon Hinyokika Gakkai Zasshi. 1991 Feb;82(2):246-53. doi: 10.5980/jpnjurol1989.82.246.

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Crystallisation of calcium oxalate dihydrate in normal urine in presence of sodium copper chlorophyllin.在叶绿酸铜钠存在的情况下,正常尿液中草酸钙二水合物的结晶。
Urol Res. 1982;10(4):173-6. doi: 10.1007/BF00255940.
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