叶绿酸铜钠对大鼠肾脏草酸钙晶体形成的影响。
Effect of sodium copper chlorophyllin on the formation of calcium oxalate crystals in rat kidney.
作者信息
Tawashi R, Cousineau M, Sharkawi M
出版信息
Invest Urol. 1980 Sep;18(2):90-2.
PMID:7053081
Abstract
We induced the deposition of calcium oxalate crystals in rat kidney by intraperitoneal administration of 4-hydroxy-L-proline or sodium oxalate and studied the amounts and size distribution characteristics of the deposited crystals. Intravenous administration of sodium copper chlorophyllin inhibited the deposition and growth of calcium oxalate crystals induced by 4-hydroxy-L-proline or sodium oxalate. This finding may be of importance in calcium oxalate urolithiasis.
摘要
我们通过腹腔注射4-羟基-L-脯氨酸或草酸钠诱导大鼠肾脏中草酸钙晶体的沉积，并研究了沉积晶体的数量和大小分布特征。静脉注射叶绿酸铜钠可抑制由4-羟基-L-脯氨酸或草酸钠诱导的草酸钙晶体的沉积和生长。这一发现可能对草酸钙尿路结石具有重要意义。
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