Shneyour Y, Koltin Y
Mutat Res. 1983 Jan;107(1):41-51. doi: 10.1016/0027-5107(83)90077-5.
A strain with an elevated level of spontaneous mutations and an especially high rate of reversion at a specific locus (pab-) was identified. The mutator trait is recessive. UV sensitivity and the absence of a UV-specific endonucleolytic activity were associated with the enhancement of the mutation rate in mutator strains. The endonuclease associated with the regulation of the mutation rate also acted on single-stranded DNA. The molecular weight of this enzyme is about 38000 daltons.
鉴定出一种自发突变水平升高且在特定基因座（pab-）处回复突变率特别高的菌株。突变体性状是隐性的。紫外线敏感性以及缺乏紫外线特异性内切核酸酶活性与突变体菌株中突变率的提高有关。与突变率调节相关的内切核酸酶也作用于单链DNA。这种酶的分子量约为38000道尔顿。
