Suárez de Lezo J, Carrasco J L, Pasalodos J, del Rio A, Sobrino J A
Eur J Cardiol. 1978 Apr-May;7(2-3):219-37.
The relationship between the ascending slope of the apexcardiogram (ACG) and direct determination of left ventricular (LV) performance as assessed angiographically by measurement of the ejection fraction (EF), mean velocity of circumferential fiber shortening (mVcF), mean normalized systolic ejection rate (MNSER), and percentage of the systolic shortening of ventricular long axis (%L), were studied in 40 patients with a wide variety of cardiac diseases. The ascending slope correlated closely and significantly (P less than 0.05) with all of them: (1) EF (r = 0.774), (2) mVcF (r = 0.776), (3) MNSER (r = 0.767) and (4) %L (r = 0.668). In a control group of 10 normal subjects, phi was determined and compared with that obtained in patients with depressed LV function, the difference being statistically significant (P less than 0.01). Other noninvasive indices derived from simultaneous phono-mechano-cardiographic readings were also studied. The calibrated ACG did not correlate with any of the hemodynamic indices; however the calibrated carotidogram did correlate with the peak systolic aortic pressure (r = 0.503). The ratio preejection period/left ventricular ejection time correlated significantly, but less than previously reported with the EF (r = 0.574). We conclude that the value of phi leads to additional evidence supporting the use of quantitative ACG as a noninvasive measure of LV performance in patients with cardiac disease.
在40例患有各种心脏疾病的患者中，研究了心尖搏动图（ACG）的上升斜率与通过测量射血分数（EF）、圆周纤维平均缩短速度（mVcF）、平均标准化收缩期射血率（MNSER）和心室长轴收缩期缩短百分比（%L）进行血管造影评估的左心室（LV）功能直接测定之间的关系。上升斜率与所有这些指标密切且显著相关（P<0.05）：（1）EF（r = 0.774），（2）mVcF（r = 0.776），（3）MNSER（r = 0.767）和（4）%L（r = 0.668）。在10名正常受试者的对照组中，测定了phi并与左心室功能降低患者的phi进行比较，差异具有统计学意义（P<0.01）。还研究了从同步心音 - 机械心动图读数得出的其他非侵入性指标。校准后的ACG与任何血流动力学指标均无相关性；然而，校准后的颈动脉图与收缩期主动脉压峰值相关（r = 0.503）。射血前期/左心室射血时间比值与EF显著相关，但相关性低于先前报道（r = 0.574）。我们得出结论，phi值为支持将定量ACG用作心脏病患者左心室功能的非侵入性测量方法提供了更多证据。
